Cryogenic CO2 use has skyrocketed in the past five years and will continue to grow. It is not a surprise to see that our response to these events has also gone up. CO2 response can be a killer to both civilianss and first responders unaware of its presence or dangers. Our course uses chemical and physical properties, metering, PPE selection, and Container and systems formalization to provide a foundation for safe and effective responses to these emergencies